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Semaglutide is a glucagon like peptide-1 receptor agonist (GLP-1 RA), whose role in the central nervous system is mainly reflected in reducing food intake by regulating appetite, thereby achieving weight loss.Semaglutide can act on the hypothalamus and hindbrain regions of the brain, which are important centers for appetite regulation. Specifically, it stimulates the activity of…
Editor of the Peptide Biochemistry Content Team On November 20, 2023, the CDE official website announced that Amgen’s Class 1 new drug AMG 133 has obtained implied clinical trial approval in China and is intended to be developed for weight control. AMG 133 is a potential “first in class” antibody peptide conjugate drug under development,…
If you are pregnant or about to become pregnant, you need to know the following information about using GLP-1 drugs to treat type 2 diabetes or obesity. Glucagon like peptide 1 (GLP-1) receptor agonists, such as Ozempic (semaglutide) and Trulicity (dulaglutide), are increasingly used to treat type 2 diabetes and, in some cases, to lose…
Edited by the Peptide Biochemical Content Team On June 25, 2024, Novo Nordisk announced that the new indication for Semaglutide Injection has been approved for marketing by the National Medical Products Administration (product name: Novo Nordisk) ®）， As an adjunctive therapy for a low calorie diet and increased physical activity, it is used in adult…
What are the ingredients and mechanism of action of Semagglutide?Semaglutide is a human glucagon like peptide-1 (GLP-1) analogue produced by brewing yeast cells through genetic recombination technology. Its chemical name is N ε 26 [(S) – (22, 40 dicarboxylic acid-10, 19…]. The mechanism of action of Semaglutide mainly includes the following aspects: Promoting insulin synthesis…
Semaglutide is a GLP-1 analogue with 94% homology to the human GLP-1 sequence. As a GLP-1 receptor agonist, it binds to the GLP-1 receptor and initiates a series of hypoglycemic events, including stimulating insulin secretion and reducing glucagon secretion. In addition, Semaglutide can repair damaged intima, enhance endothelial function, and be beneficial to the cardiovascular…
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